HELICOBACTER PYLORI ERADIKATSION TERAPIYASINING ICHAK MIKROBIOTSENOZIGA TA’SIRI

Qodirova Saodat Rahimjonovna

Tibbiyot xodimlarining kasbiy malakasini rivojlantirish markazi Gastroenterologiya va fizioterapiya kafedrasi dotsenti

https://orcid.org/0009-0009-0720-7702

Keywords: Helicobacter pylori, eradikatsion terapiya, antibiotikoterapiya, ichak mikrobiotsenozi, disbioz, probiotik, mikroflora, immunitet.

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Abstract

Ushbu ilmiy tezisda Helicobacter pylori infeksiyasini davolashda qo‘llaniladigan eradikatsion terapiyaning ichak mikrobiotsenoziga ta’siri o‘rganildi. Antibiotikoterapiya fonida ichak mikroflorasida yuzaga keladigan disbiotik o‘zgarishlar, foydali mikroorganizmlarning kamayishi hamda shartli-patogen flora faollashuvi tahlil qilindi. Tadqiqot natijalariga ko‘ra, eradikatsion terapiya ichak mikrobiotasining sifat va miqdor tarkibida sezilarli o‘zgarishlarni yuzaga keltirib, bifidobakteriyalar va laktobakteriyalar sonining kamayishiga sabab bo‘ladi. Shu bilan birga, disbioz natijasida meteorizm, diareya, immunitetning susayishi va metabolik buzilishlar kuzatildi. Probiotiklar hamda fizioterapevtik usullarni kompleks qo‘llash mikrobiotsenozni tiklashda samarali ekanligi aniqlandi.

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